EARLY DIAGNOSIS OF LEFT VENTRICULAR RELAXATION AND FILLING ABNORMALITIES IN ACUTE MYOCARDIAL INFARCTION: A DOPPLER ECHOCARDIOGRAPHY STUDY

*Dr. Syed Fasih Ahmed Hashmi, Dr. Mashooq Ali Dasti, Dr. Akber Yousfani, Dr. Sumera Bukhari, Dr. Javeria Samejo, Dr. Zaheer Ahmed and Dr. Zulfiqar Ali Qutrio Baloch

ABSTRACT

OBJECTIVE: To assess left ventricular diastolic function in patients treated with thromobolyric therapy for ST elevation myocardial infarction and their outcomes within 2 weeks. PATIENTS AND METHODS: This study was conducted at department of cardiology Liaquat University Hospital Hyderabad From august 2015 To October 2015. Total of 65 Patients with first episode of ST elevation of myocardial infarction received thrombolytic therapy, had risk factors for ischemic heart disease were recruited. Myocardial infarction was considered according to the WHO criteria while echocardiography was done to measure various parameters whereas the data was entered and analyzed in SPSS version 16. RESULTS: Out of 70 patients studied 14 had normal, 34 patients had impaired relaxation, 5 patients had pseudo-normalization, 4 patients reversible and 3 patients irreversible restrictive filling on the day of admission. In those patients with prolonged IVRT, reversal of E/A, increased E-DT were indicating impaired relaxation pattern. Decreased E-DT and tissue Doppler imaging detected restrictive filling pattern of diastolic dysfunction. During the 14 days of follow up period patients had developed complications in the form of longer period of stay in hospital, aarhythmias, heart failiure and death .2 patients who were admitted with STEMI in restrictive filling pattern died on the 2nd and 4th day of admission. CONCLUSION: This study helps in early diagnosis of left ventricular filling and relaxation abnormalities and their severity. It also helps in monitoring of patients, early detection of complications, management and prognosis.

Keywords: Left ventricular, acute myocardial infarction and Doppler echocardiography.