EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

THE FEATURES OF THE IMMUNE STATUS OF CHILDREN WITH CHRONIC OBSTRUCTIVE BRONCHITIS ON THE BACKGROUND OF CYSTIC FIBROSIS

Fayzullaeva N.Ya.*, Shamsiev F.M. and Musakhodjaeva D.A.

ABSTRACT

Background: Despite of the complex organization and the perfection of the defense mechanisms of the mucous membranes, various pathogens overcome all barriers and penetrate into the internal environment of the body and cause disease. This may contribute to a variety of internal and external factors that have an adverse effect on the mucous membranes of the respiratory tract and its defense mechanisms. Objective: The aim of the study was to examine the features of immunological reactivity in chronic obstructive bronchitis in children with and without cystic fibrosis. Methods: Determined lymphocytes with CD3, CD4, CD8, CD16, CD20, CD25, CD HLA-DR, CD95 phenotypes. It was held an examination of 56 children with chronic obstructive bronchitis (COB). Of these, In 18 children experienced COB on the background of cystic fibrosis. Result: Carried immunological studies have shown that the presence of cystic fibrosis exacerbate immunodeficiency Children with COB, who significantly reduced the level of T-lymphocytes and subpopulation of CD4 + - and CD8 + cells, while the level of B lymphocytes was increased. Conclusion: The results showed that the development of immunopathological conditions in children with chronic obstructive bronchitis on the background of cystic fibrosis has its own characteristics, and to a greater extent due to the insolvency of a functional immune cells.

Keywords: Chronic obstructive bronchitis, cystic fibrosis, immune system.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )