PATTERN OF ANTIBIOTIC THERAPY AND EFFECTIVENESS IN GASTROINTESTINAL SURGERIES

Ibel C. Fredy*, Santosh Chandrasekhar, R. Srinivasan and Lohith K. B.

ABSTRACT

Surgical site infection is one of the most common healthcare-associated infection in patients undergoing surgery and remains a major source for post-operative morbidity. This encourages surgeons to adopt a more liberal approach toward prescribing antibiotics. In practice this may seem beneficial in reducing infection rates in inpatient setting, but can potentially lead to emergence of more resistant microorganisms. Thus, resulting in worsening of patient condition as well as increased health-care costs. Purpose of our study is to identify pattern of antibiotic usage in various GI surgeries and its effectiveness. It is a cross-sectional Retrospective study. Data analyzed by Microsoft excel. Appropriateness of antibiotic therapy was evaluated based on compliance with ASHP Therapeutic Guidelines and response to the treatment Over the study period, a total of 652 patient profiles were collected. Surgical procedures performed were appendectomy (45, 6.90%), gastroduodenal procedures (141, 21.66%), laparoscopic procedures (104, 15.97%), small intestine obstruction removal (23, 3.53%), hernia repair (86, 13.21%), colorectal procedures (150, 23.04%), cancer surgery (38, 5.84%), hepatic surgeries (31, 4.75%) and other (33, 5.10%). The antibiotic therapy for the above procedures was compared with American Society of Health-System Pharmacists therapeutic guidelines and found to have lack of adherence to the guidelines.

Keywords: Surgical Site Infection, Antibiotics, Gastrointestinal Surgeries.