EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

EVALUATION OF ANTIMICROBIAL ACTIVITY OF LEAVES OF GARCINIA GUMMI GUTTA - A PLANT OF ETHNOMEDICINAL IMPORTANCE

*Lincy Sara Varghese, Shehma Shukkoor, Jaina P. James, Beena Habel, Aiswarya Tom and Shalia Joseph

ABSTRACT

Garcinia gummi gutta Linn. is a plant of immense importance in ethnobotany. The plant has been used by the tribes singly or in combination with other plant parts to cure various ailments. The present study investigated the antibacterial activity of aqueous, acetone and methanolic extracts of leaves of G. gummi gutta on eight bacterial strains viz Staphylococcus aureus, Salmonella typhi, Salmonella typhimurium, Bacillus sp., Proteus sp., Klebsiella sp., Serratia sp. and Pseudomonas sp. and two fungal stains viz. Aspergillus and Penicillium, respectively. All the three extracts potentially inhibited the growth of the test bacteria. However, the acetone extract was superior in antibacterial activity, followed by the methanol and aqueous extracts. Significant antibacterial activity was observed against S. aureus, Bacillus sp. and Serratia sp. In the antifungal assay the aqueous extract exhibited minimal antifungal activity against Penicillium sp., but did not inhibit the growth of Aspergillus sp. Acetone extract inhibited the growth of Aspergillus alone, without having any inhibitory activity on Penicillium sp. Methanol extract inhibited the growth of both the test fungi.

Keywords: Garcinia gummi gutta, secondary metabolites, antibacterial activity, antifungal activity, ethnomedicine.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia