EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

ANTIBACTERIAL ACTIVITY OF PSIDIUM GUAJAVA L. LEAVES EXTRACTS AGAINST SOME GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA

Gitika and Manoj Kumar*

ABSTRACT

Antibacterial efficiency of Psidium guajava L. leaves extracts in different solvents (methanol, ethanol and aqueous) were studied against seven different bacterial strains, including four gram-positive (Micrococcus luteus, Bacillus subtilis, Staphylococcus aureus and Streptococcus sp.) and three gram-negative bacterial strains (Escherichia coli, Pseudomonas aeruginosa and Salmonella typhimurium) using agar well diffusion assay (AWDA) method. In the present study, aqueous extract gave the highest yield percentage as compared to methanol as well as ethanol extracts. The patterns of inhibition varied with the solvent as well as the tested microorganisms. The results showed that M. luteus among the gram-positive and E. coli among the gram-negative were highly susceptible as compared to other tested organisms. The methanol extract of P. guajava was the most effective as the widest inhibitory zone was observed as compared to the ethanol and aqueous extracts. The minimum inhibitory concentrations (MIC) as well as the minimum bactericidal concentration (MBC) of the crude leaves extracts were determined for the various organisms which ranged between 12.5 to 100 mg/ml. The remarkable antibacterial activity of the leaves extracts against tested gram-positive and gram-negative bacteria suggests that the P. guajava plant leaves could be a possible source of novel broad spectrum drug for treating infectious diseases.

Keywords: Antibacterial; Psidium guajava; Solvents; Zone of Inhibition.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia