OPTIMIZATION OF CULTURAL CONDITIONS FOR IMPROVED PRODUCTION AND BIOACTIVE METABOLITES BY ASPERGILLUS NIGER (MTTC-961)
Kalyani P., Geetha S.* and Hemalatha K. P. J.
The purpose of the present study was to investigate the influence of cultural conditions and environmental parameters affecting the growth and bioactive metabolite production of the fungi Aspergillus niger (MTTC-961) which exhibits a broad spectrum of in vitro antibacterial activity against human infecting bacterial pathogens and the high bioactive metabolites production was observed in potato dextrose broth, compared to the other media. Fructose and yeast extract were found to be a best and most suitable carbon and nitrogen sources respectively, for the optimum growth and production of bioactive metabolites. Maximum bioactive metabolite productions occur in pH of 6 and temperature at 30°C for 144hr of incubation.
Keywords: Aspergillus niger, Bioactive metabolite production, Optimization.
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