EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , Doi-Digital Online Identifier , ISSN National Centre , Zenodo Indexing , International CODEN Service, USA , 

 ISSN (O) : 2394-3211

 ISSN (P) : 3051-2573

Impact Factor: 8.158

 ICV - 79.57

Abstract

RECURRENT FUNGATING ANAPLASTIC MENINGIOMA: A CASE REPORT

Dr. Mahmood Al Hatali, Dr. Simin Laiq, Dr. Zahra Al Hajri, Dr. Aziz Haris, Dr Aiman Al Salmi, Dr. Livingston C., Dr. Fahad Al Khadr, Dr. Ahmed Wadee, Dr. Kaurher Al Zakwani, Dr. Yaqoob Al Saidi, Dr. Arshad Kabir Khan, Dr Sadia Durrani, Dr. Neeraj Salhotra*

ABSTRACT

Anaplastic meningioma, CNS WHO grade 3, is a rare and aggressive tumor characterized by a high risk of local recurrence and poor prognosis. Maximal safe surgical resection followed by radiotherapy remains the mainstay of treatment, while effective systemic chemotherapy for recurrent disease remains limited. We report an unusual case of recurrent meningioma presenting as a large fungating scalp mass. A 50-year-old man presented in 2022 with headache, seizures, and right-sided weakness. Imaging revealed a large right parietal extra-axial mass extending across the midline. He underwent craniectomy and tumor excision; complete removal was limited by venous sinus involvement, and residual tumor remained along the sinus. Initial histopathology showed an atypical meningioma, CNS WHO grade 2. Radiotherapy was advised, and subsequent imaging demonstrated progressive residual disease. Further surgery was initially declined. By August 2026, the tumor had progressed to a large fungating scalp mass with a small intracranial component. Palliative resection was subsequently performed, followed by reconstruction with a rotation flap and skin graft. Histopathology now demonstrated an anaplastic meningioma, CNS WHO grade 3. The postoperative course was uneventful, and palliative radiotherapy was advised. This case highlights the potential for aggressive local progression and histopathological transformation of recurrent atypical meningioma and emphasizes the importance of early multidisciplinary management.

Keywords: Anaplastic meningioma; atypical meningioma; CNS WHO grade 3; recurrent meningioma; fungating tumor; scalp.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia Doi-Digital Online Identifier ISSN National Centre Zenodo Indexing International CODEN Service, USA

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