EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN (O) : 2394-3211

 ISSN (P) : 3051-2573

Impact Factor: 8.158

 ICV - 79.57

Abstract

ENDOCATOR AND ATP BIOLUMINESCENCE TECHNOLOGY: A NOVEL PARADIGM FOR OBJECTIVE ASSESSMENT OF ROOT CANAL DISINFECTION – A REVIEW ARTICLE

Dr. Sahadev Chickmagaravalli Krishnegowda, Dr. Sandeep Rudranaik, Dr. Bharath M. J.,
Dr. Raghu Kachenahalli Narasimhaiah, Dr. Rakshith Jayanna, Dr. Likitha Venkatesh*

ABSTRACT

The success of endodontic treatment depends largely on the effective elimination of microorganisms, necrotic tissue remnants, and organic debris from the root canal system. Despite significant advances in instrumentation and irrigation protocols, clinicians still lack an objective chairside method to verify canal cleanliness before obturation. Currently available assessment techniques, including microbial culture, polymerase chain reaction, and microscopic analysis, are predominantly research-based tools and are not routinely applicable in clinical practice. Recently, ATP bioluminescence technology has emerged as a promising method for rapid assessment of residual biological contamination within root canals.[1,10,11] Endocator is a novel ATP-based chairside diagnostic system that measures ATP-related bioluminescence signals to quantify residual biological material and generate an objective cleanliness score.[1,5] This narrative review discusses the biological basis of ATP bioluminescence, the operating principle of Endocator, currently available laboratory and clinical evidence, potential applications in endodontic practice, advantages, limitations, and future directions.[1-5] Current evidence suggests that ATP-based assessment may enhance clinical decision-making by providing an objective measure of root canal cleanliness before obturation.[1]

Keywords: Endocator, ATP bioluminescence, root canal disinfection, canal cleanliness, microbial assessment, endodontics.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia Doi-Digital Online Identifier ISSN National Centre Zenodo Indexing International CODEN Service, USA

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