EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , Doi-Digital Online Identifier , ISSN National Centre , Zenodo Indexing , International CODEN Service, USA , 

 ISSN (O) : 2394-3211

 ISSN (P) : 3051-2573

Impact Factor: 8.158

 ICV - 79.57

Abstract

ENHANCING GINGIVAL AESTHETICS: MICRO-NEEDLING WITH TOPICAL VITAMIN C FOR DEPIGMENTATION -A IN VIVO CLINICAL STUDY

*Dr. Pradnya Gaikwad, Dr. Mona Shah, Dr. Rasika Painter, Dr. Vishnu Maske

ABSTRACT

Background: Aesthetics is vital in dental treatment, emphasizing cosmetic outcomes alongside functionality. Healthy gums are crucial for an appealing smile, but conditions like gingival melanin hyperpigmentation can negatively affect aesthetics, prompting interest in cosmetic procedures. While various depigmentation methods are available, they often have drawbacks such as pain and recurrence. Newer techniques like micro-needling and vitamin C mesotherapy show promise for reducing pigmentation and enhancing tissue quality, thereby improving patient satisfaction. The study aims to assess the effectiveness of micro-needling for treating gingival hyperpigmentation. Materials and methods: In a study involving 30 patients with gingival depigmentation, a pre-operative phase included thorough medical histories, clinical exams, periodontal treatment, and baseline measurements. Key clinical characteristics evaluated were gingival pigmentation, discomfort, and wound healing. Each patient underwent scaling and root planning, followed by a surgical procedure with micro-needling and ascorbic acid paste application. Follow-up assessments at baseline, 2, 4, and 12 weeks measured pigmentation, discomfort, wound healing, and included clinical photography. Results: Results showed a significant reduction in pigmentation scores over 12 weeks when analyzed using Friedman’s test with statistically significant differences in DOPI and WHI across multiple time intervals, attributed to micro-needling enhancing vitamin C absorption and its anti-melanogenic properties. Postoperative discomfort was minimal, and most patients reported high satisfaction with the results. Conclusion: The study highlights that the positive results can be linked to the combined effects of micro-needling and topical vitamin C, positioning this treatment as a minimally invasive, cost-effective, safe, and clinically effective option for gingival depigmentation.

Keywords: Gingival aesthetics, Micro-needling, Depigmentation, Vitamin C ,Gingival wound healing.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia Doi-Digital Online Identifier ISSN National Centre Zenodo Indexing International CODEN Service, USA

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