REVIEW ON THE FORMULATION AND EVALUATION OF ORO DISPERSIBLE TABLETS

B. Mugundhan*, D. Sudhan

ABSTRACT

Advances in pharmaceutical technology have led to the development of innovative drug delivery systems aimed at improving therapeutic efficacy and patient compliance. Among oral dosage forms, tablets remain the most commonly prescribed and administered formulations due to their convenience, accurate dosing, and cost-effective production. However, difficulties in swallowing conventional tablets among pediatric, geriatric, and dysphasia patients have prompted the development of Orodispersible Tablets (OD's), which offer rapid disintegration and ease of administration without the need for water. Tablets are solid dosage forms containing one or more active pharmaceutical ingredients (API s), with or without suitable excipient, and are prepared by compression or moulding methods. Depending on the manufacturing process, tablets can be broadly classified into compressed tablets and mould-ed tablets. Compressed tablets may be further categorized into directly compressible tablets, chew-able tablets, tablet triturates, and other specialized forms. In recent years, Orodispersible Tablets(ODTs) have gained significant attention as an advanced oral drug delivery system. These tablets are designed to disintegrate rapidly in the mouth, usually within a few seconds, without the need for water. DTs offer several advantages, including improved patient compliance, ease of administration for pediatric, geriatric, and dysphasia patients, rapid onset of action, and enhanced convenience. Owing to these benefits, the formulation and evaluation of or orodispersible tablets have become an important area of pharmaceutical research and development.

Keywords: Orodispersible tablets, Etoricoxib, Natural Superdisintergrant.