FORMULATION AND EVALUATION OF CASSIA AURICULATA HERBAL ORAL DISSOLVING FILM FOR EFFECTIVE MANAGEMENT OF DIABETES MELLITUS

*Chatur Rohidas Rajendra, Kahandal Vishal Shankar, Jadhav Mayuri Dattu, Prof. Pawara Chetan Sir

ABSTRACT

Diabetes mellitus is a metabolic disease with a condition where an individual has high levels of sugar content in his/her blood because of a lack of insulin production. There are many traditional medicines that are available for the treatment of diabetes mellitus, but most of them have problems such as low patient compliance, gastrointestinal disorders, and difficulty in swallowing solid dosage forms. There are many studies that show that herbal medicines are very useful for treating chronic diseases, and one such medicinal herb is Cassia auriculata, which is very effective for antidiabetic, antioxidant, and hepatoprotective effects. This study focuses on the preparation and evaluation of oral dissolving films (ODFs) loaded with Cassia auriculata extract by the solvent casting technique. The films produced are evaluated based on their physiochemical properties, dissolution, and disintegration rate. Conclusion: The results show that Cassia auriculata-loaded oral dissolving films are promising alternatives for treating diabetes mellitus.

Keywords: Cassia auriculata, diabetes mellitus, oral dissolving films, herbal drug delivery and antidiabetic activity.