ARTIFICIAL INTELLIGENCE IN THE PHARMACEUTICAL INDUSTRY: APPLICATIONS, FUTURE OF CLINICAL PHARMACY CHALLENGES AND TECHNOLOGY DRUG DELIVERY DESIGN

Adarsh Pratap Singh, Sandeep Prakash*, Saurabh Kumar, Neha Gautam, Firdous Bano, Harshit Gupta, Lavkush Maurya, Sandeep Kumar, Sneh Lata, Ajay Kmar

ABSTRACT

Artificial intelligence (AI), machine learning (ML), and deep learning (DL) are gaining increased interest in many fields, into pharmaceutical Research has catalyzed transformative advancements across drug discovery, clinical development, manufacturing, and postmarket surveillance. This review comprehensively examines AI's role in modern pharmacotherapy, beginning with its historical evolution in life sciences and progressing to cutting-edge applications such as AlphaFolddriven protein modeling, natural language processing (NLP) for biomedical literature mining, and AIaugmented pharmacovigilance. Methodologically, we synthesize interdisciplinary insights from peer-reviewed literature (2013–2026), highlighting innovations in cheminformatics (e.g., QSAR, RDKit), predictive toxicology, and personalized medicine. Case studies illustrate AI's capacity to compress drug development timelines, as seen in COVID-19 repurposing efforts and de novo kinase inhibitor design. However, challenges persist, including algorithmic bias, regulatory ambiguities, and the “black-box” nature of deep learning models. By critically evaluating successes and limitations, this review underscores AI's potential to redefine pharmaceutical innovation while advocating for robust frameworks to ensure ethical, transparent, and clinically translatable AI deployment

Keywords: Artificial intelligence in pharmacy drug discovery; Applications, Future of clinical Pharmacy Challenges And Technology drug delivery design , optimization; AI-driven healthcare.