REVIEW ON PHYTOPHARMACOLOGY OF DIFFERENT PARTS OF MANILKARA ZOPATA

Swapnali Satish Kasture*, Aarti Aanat Varne, Priti Prakash Mastud

ABSTRACT

A well-known member of the Sapotaceae family, Manilkara zapota, also known as Sapodilla, Chikoo, or Sapota, is utilized for traditional medicinal reasons worldwide. It is a well-known commercial crop that is widely grown in Sri Lanka, Indonesia, India, and Malaysia. Numerous phytochemicals have been extracted from different portions of the plant, and various parts of the tree have historically been employed to cure illnesses like dysentery, fever, and diarrhea. This paper provides a summary of the botanical, taxonomical, pharmacological, and phytochemical components of Manilkara zapota. The plant's bioactivities, including its antibacterial activity, antidiabetic, anti-inflammatory, antidiarrheal, anthelmintic, anticancer, and antarthritic qualities, are also covered in this page. Multiple researchers have documented a plethora of phytoconstituents derived from the plant, contributing to a spectrum of biological impacts, such as anti-inflammatory, arthritics, antibacterial, antifungal, antioxidant, antitumor, and antidiabetic effects, as well as central nervous system (CNS) depressant action. Additionally, the extensive use of other plant parts, including as leaves, fruit, and seeds, was covered in this review. Antioxidants and phytochemicals are among the many bioactive substances found in M. zapota leaves. Investigating its chemical composition can assist find molecules that may have neuroprotective or anti-inflammatory properties related to Parkinson's disease. Antioxidants found in M. zapota leaves may lessen oxidative damage to neurons and delay the onset of illness.

Keywords: Manilkara zapota, Traditional Uses, Phytochemistry, Pharmacology.