SYNTHESIS AND STRUCTURAL ELUCIDATION OF A COBALT(II) COMPLEX DERIVED FROM 2,2?-((1E,1?E)-(ETHANE-1,2-DIYLBIS(AZANYLYLIDENE))BIS(3-PHENYLPROPAN-1-YL-1-YLIDENE))DIPHENOL AND ITS ANTIBACTERIAL AND ANTIFUNGAL ASSESSMENT

Ramnath Andhale*, Suhas Janwadakar, Dilip Yadav, Anand Malankar, Jaiba Shaikh

ABSTRACT

Preparation of Metal Complex Of newly synthesized Schiff base that 2-2’((1E,1’E-(ethane-1,2-diylbis(azanylylidene)) bis(3-phenylpropan-1-yl-1-ylidene)) diphenol using 2-hydrxy-3- phenylpropiophenone and ethylenediamine and then react with cobalt chloride hexahydrate salt to form unique metal complex were characterized by different physicochemical studies like FTIR, H1& C13 NMR,mass spectroscopy, P-XRD, determine the metal content by using ICP-OES. Examination of the antibacterial and antifungal properties of the metal complex of schiff base. They exhibit promising activity. The Successful Synthesis, structural characterization and notable biological activities of the compound underscore its pharmaceutical potential. Additional research is necessary to enhance its bioactivity and investigate its therapeutic applications.

Keywords: Schiff base, metal complex, 2-hydroxy-phenylpropiophenone, Cobalt chloride hexahydrate, ethylenediamine, antibacterial activity, Antifungal anctivity.