EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , Doi-Digital Online Identifier , ISSN National Centre , Zenodo Indexing , International CODEN Service, USA , 

 ISSN (O) : 2394-3211

 ISSN (P) : 3051-2573

Impact Factor: 8.158

 ICV - 79.57

Abstract

PERFUME ALLERGENS IN THE GCC MARKET: CHEMICAL CHARACTERIZATION, HEALTH RISKS, AND REGULATORY ALIGNMENT

Pooja Thanki, Sudhir Sawarkar*, Kishore Machale

ABSTRACT

This research paper examines the presence, risks, and regulation of perfume allergens in the Gulf Cooperation Council (GCC) market. Perfumes are deeply embedded in the region’s culture and daily life. Still, growing evidence shows they can cause allergic reactions—ranging from skin irritation and respiratory discomfort to, in rare cases, severe responses like anaphylaxis. To explore this issue, we employed a multidisciplinary approach that included market analysis, chemical testing using Gas Chromatography-Mass Spectrometry (GC-MS), case reviews, and a comparison of international and regional regulations. Our findings indicate that the GCC fragrance industry is experiencing rapid expansion, driven by high consumer spending, cultural preferences, and demand for luxury and halal-certified products. Chemical analysis of popular perfumes and deodorants revealed several known allergens—such as limonene, linalool, citral, eugenol, and coumarin—present in varying concentrations across brands. Case studies from the EU, USA, and Saudi Arabia highlight the widespread nature of fragrance-related allergies. This study highlights the need for harmonized implementation across the GCC region. Although GSO 1943 is largely aligned with the European Cosmetics Regulation EC 1223/2009—adopting similar lists of prohibited ingredients, UV filters, preservatives, and labeling requirements, the actual implementation varies significantly among member countries. Each GCC nation maintains its own registration or notification system, requiring companies to navigate distinct approval processes.[1] This fragmented approach undermines the benefits of a unified regulatory framework and poses challenges for consistent enforcement and public awareness. Testing methods such as patch testing and lab-based assays remain essential for identifying allergens and assessing product safety. Additionally, clearer labelling of allergenic ingredients and stronger public education. It also encourages the development of fragrance-free and hypoallergenic alternatives, along with continued research to improve safety and transparency in the GCC fragrance market.

Keywords: Perfume Allergens, Fragrance Sensitivity, GCC Market, GC-MS Analysis, Regulatory Standards, Hypoallergenic Products.


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