WOUND HEALING ACTIVITY OF METHANOLIC EXTRACT OF THE PEEL OF ABELMOSCHUS ESCULENTS
P. Senthil Kumaran*, A. Sumathi, K. R. Shanthini and J. Mallika
The history of medicine is as that old as human civilization. Nature is provided a complete storehouse of remedies to cure all ailments of mankind. Among the biotic and abiotic elements of nature, they plants are indispensable to man as they provide food, clothing and shelter the three important necessities of life along with other useful product us medicines to alleviate his suffering from injury and disease. The preliminary phytochemical analysis was carried out in the methanol extracts. It was found that glycosides, Carbohydrate, amino acids and tannins. The methanol extract was screened for wound healing activity by excision and incision wound model, in the form of an ointment having 2 concentrations (10%and 20 % w/w) of peel extract in simple ointment base. Both the concentrations of the methanol extract showed significant response in both the wound types tested when compared with the control group. Povidine ointment (0.2%w/w) was used as an standard drug. The extract having significant (p>0.05 and p<0.01) wound healing activity compared to control. On the basis of the results obtained suggest marked that extracts have significant wound healing activity of Abelmoschus esculents. The results supported the traditional use of this plant in some painful and wound healing conditions.
Keywords: Abelmoschus esculents, Phytochemical screening, wound healing.
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