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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57



*Vd. Sachin Sonappa Dargu, Vd. Suryakant Dattatray Rokade, Vd.Chandrashekhar Dattatray Vaikos, Vd. Manisha Kishanrao Dawre, Vd. Prashant Gopinath Sali and Vd. Pradnya Ravindra Deshpande


Rectal route delivery is an efficient alternate to oral and parenteral route in partial avoidance to first pass metabolism. In Ayurveda, panchkarma therapy is usually carried out for samsodhan and samsaman. This therapy includes vaman, virechan, basti, nasya, raktmokshan. Basti karma includes niruha (shodhan) and anuvasana (saman). Classical literature attaches a great significance to this form of treatment. Anuvasan basti includes Matra basti in which there is use of till tail in single or medicated form. Anuvasan basti has no harmful effect even if staying in body. Rectum has sub mucosal fold called valves of Houston. Has no villa, epithelium layer is one cell thick, composed of cylindrical and goblet cells which secrets mucus. Absorption of drugs from epithelium involves transcellular route depends on lipophilicity. Intestinal absorption of fatty acids depends on the partition coefficient. Efficacy of Anuvasana basti definitely depends on its local action. For that purpose one should know the affinity of fatty acids present in till tail towards the mucus membrane of intestine. The present work is done to study the factors affecting the affinity of fatty acids with respect to structure of mucosa of intestine.

Keywords: Pakwashaya, Vata dosha, Anuvasana Basti, Mucosa of rectum-1) Partition Coefficient 2) Absorption barrier, Fatty acids in White till tail.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia