“EXPLORING THE ANTIMICROBIAL EFFICACY OF 2-AMINO BENZAMIDE DERIVATIVES AGAINST PATHOGENIC MICRO-ORGANISUMS”

*Rakshitha A. R.,Pramila T.

ABSTRACT

A series of new 2-aminobenzamide derivatives (2a-2i) has been synthesized in good to excellent yields by adopting
conventional methodologies starting from 2-amino salicylic acid and characterized on the basis of their analytical
and spectral. Selected compounds of this series were then tested antimicrobial activity against different strains of
gram positive and gram-negative bacteria and fungal strain by using cup plate method. among this series of
compounds 2f shows broad spectrum antibacterial activity. Whereas, the tested compounds 2d and 2e and exhibited
moderate activity. and compound 2c shows good activity against gram negative bacteria. For antifungal activity
compounds 2g shows potent activity. whereas the test compounds 2f and 2i exhibited moderate activity,

Keywords: 2-Amino Benzamide, Antibacterial activity, Antifungal activity. Cup plate method.