RENO-PROTECTIVE POTENTIAL OF ETHANOLIC HERBAL EXTRACTS AGAINST GENTAMICIN CHALLENGED ALBINO WISTAR RATS

*Dr. Mehnoor Farheen, Dr. D. Ramakrishna, Asmaa, Syeda Qadar Unnisa, Dr. Abdul Aziz Shahid, Khadija Ameen

ABSTRACT

Renotoxicity could be a usual disorder characterized as a fast decrease in kidney work coming about in irregular maintenance of Sr creatinine and blood urea, which should be excreted. There are usual chemical operators to treat intense renal disappointment. The dried roots and the entire plant of Clausena anisata and Oxalis corniculata were extracted by ethanol. the ethanolic extricate appeared factually critical renoprotective action. The plant extricate demonstrated to have renoprotective possibilities since of its known flavonoid and antioxidant character. There may be a opportunity for encourage examination on the histo pathology and medical ponders that are essential to explain the dynamic phytochemical constituents with powerful reno protective activity. The Gentamicin induced rats appeared lifted levels of Sr Blood Urea Nitrogen (BUN) and lipidperoxidation parameter like malon di aldehyde (MDA) which was essentially diminished with therapy of EECA AND EEOC, which demonstrates its Renoprotective movement.

Keywords: renoprotective agents, Clausena anisata and Oxalis corniculata.