SYNTHESIS AND CHARACTERIZATION OF 1(4-AMINOPHENYL)-2(PCHLOROPHENYL THIOCARBAMIDO)-1-ETHANOL

Ajay Balu Wadekar*

ABSTRACT

Pharmaceutically active drugs are crucial part of today’s generation. Due to huge population of the world
responsibility of the chemist increase toward produce active molecules. Thiocarbamide moieties have various
pharmaceutical and industrial significances. Present research scheme designed to synthesize 1(4-aminophenyl-2(4-
chlorophenylthiocarbamido)-1-ethanol by the interactions of 4-(2-amino-1-hydroxyehtyl) aniline and pchlorophenyl
isothiocyanate in acetone medium, to isolate 1(4-aminophenyl)-2 (p-chlorophenylthiocarbamido)-1-
ethanol. Characterized of this synthesized molecules on the basis of conventional elemental analysis, chemical
characteristics and through IR, PMR, CMR and Mass spectral analysis. Confirmed the structure of synthesized
molecule from spectral data.

Keywords: 4-(2-amino-1-hydroxyehtyl) aniline, p-chlorophenyl isothiocyanate, thiocarbamide, 1(4- aminophenyl)-2 (p-chlorophenylthiocarbamido)-1-ethanol.