FACTORS RELATING TO SKIN AGING

Jennifer Chu, M. D.*, Francis Bruyninckx, M. D. and Steven Goodman, M. D.

ABSTRACT

Our aim is to introduce new updates on skin health so that the skin can maintain health and thus youthfulness for as long as it possibly can.

The only visible damage due to aging is associated with major healing defects, and is linked partly to the alteration of the biomechanical properties of skin cells, mainly involving dermal fibroblasts.[1]

The immune system, another key component in maintaining skin homeostasis and the efficient healing of wounds, also suffers from the effects of time: the consequent skin immunosenescence which concerns a gradual deterioration of the immune system, limits anti-infectious and vaccine responses, while promoting a pro-tumor environment.[4] Senescent cells have been found to accumulate with age and may contribute to age-related skin changes and pathologies.

Keywords: .