A REVIEW ON “VARIOUS PHARMACOLOGICAL ACTIVITIES OF NOVEL ISOXAZOLES DERIVATIVES”

Kavya V.*, Namith Dev S. V., Prathiksha S. L., Ruthu, Vaishnavi M. K., Bharath S. M.

ABSTRACT

Isoxazole-containing compounds have garnered significant attention due to their versatile pharmacological profiles
and favourable physicochemical characteristics. This review emphasizes current research on novel isoxazoles, and
their therapeutic applications across a broad spectrum of biological targets. Particular focus is given to their antiinflammatory,
antioxidant, antimicrobial, antibacterial, and anticancer properties, supported by both in vivo and in
vitro evaluations. By integrating the isoxazole core into drug like scaffolds, researchers have advanced the
development of agents with improved target specificity, metabolic stability, and minimal toxicity. This
comprehensive analysis underscores the strategic value of isoxazoles in modern medicinal chemistry and highlights
promising avenues for future drug design and therapeutic innovation.

Keywords: Isoxazoles, anti-inflammatory activity, antioxidant activity, antimicrobial activity, antibacterial activity, and anticancer activity.