ROLE OF PANCHAKARMA AND AYURVEDIC MEDICINE IN CONTORLING CLD AND T2DM: A CASE STUDY

Acharya Manish, Dr. Gitika Chaudhary*, Dr. Richa, Dr. Suyash Pratap Singh, Dr. Manjeet Singh and Dr. Tanu Rani

ABSTRACT

Chronic liver disease (CLD) encompasses a wide range of hepatic disorders, including cirrhosis, hepatitis, and non-alcoholic fatty liver disease (NAFLD), which are often associated with long-term damage to liver tissue. The global burden of CLD is rising, driven by factors such as viral infections (Hepatitis B and C), excessive alcohol consumption, obesity, and metabolic syndrome. Early stages of CLD may remain asymptomatic, but as the disease progresses, it can lead to liver fibrosis, cirrhosis, liver failure, and hepatocellular carcinoma. Diagnosis is typically based on a combination of clinical symptoms, laboratory tests, imaging studies, and biopsy, while treatment strategies aim to address the underlying cause, slow disease progression, and manage complications. Advances in medical therapies and lifestyle interventions have shown promise in improving patient outcomes, but effective prevention, early detection, and management remain critical for reducing morbidity and mortality associated with CLD. Ayurveda views jaundice (Kamala) as a disorder of the raktavahastrotas, with the liver (Yakrit) and spleen (Pleeha) being its primary sites. Vitiated Pitta is the key factor in its pathogenesis. Modern medicine identifies the liver as a vital organ with a remarkable reserve capacity, where dysfunction only appears after significant damage (75-80% loss of function). Bilirubin, a yellow breakdown product of hemoglobin from aged RBCs, acts as a cellular antioxidant and is key in the pathophysiology of jaundice. Further research is essential to develop novel therapeutic approaches and to better understand the pathophysiology of the disease. Diabetes mellitus is a group of metabolic diseases characterized by persistent hyperglycemia due to defects in insulin secretion, insulin action, or both. Type 2 diabetes occurs when the body either becomes resistant to insulin or doesn't produce enough insulin. Ayurvedic literature provides a comprehensive understanding of CLD, including its prognosis, complications, and treatment. Panchakarma is an Ayurvedic detox therapy that may help manage lifestyle diseases like CLD and diabetes by detoxifying the body, balancing doshas, and improving metabolism. Here are the Panchakarma methods like Basti for CLD treatment. As a result, it was found to improve the target and outcome parameters.

Keywords: Chronic Liver Disease (CLD), Jaundice, Diabetes Mellitus, Prameha, Madhumeh, Panchakarma Chikitsa, Basti.