3D BIOPRINTING-BASED APPROACH FOR BIOENGINEERED SKIN MODELS: A NOVEL METHOD FOR DRUG TESTING AND DISEASE RESEARCH

Kunj Patel* and Nandini Jha

ABSTRACT

The emergence of 3D bioprinting has opened new frontiers in developing physiologically relevant skin models for pharmaceutical and biomedical research. Traditional approaches such as 2D cell culture and animal testing fall short in replicating the complex architecture and function of human skin. This paper outlines key bioprinting techniques, bioink selection, and cell types utilized in engineering skin constructs. Applications in drug testing, disease modeling, and wound healing are reviewed, along with current challenges and future directions. The integration of vascularization techniques, artificial intelligence, and stem cell technology highlights the potential of 3D bioprinting to transform dermatological research and personalized medicine.

Keywords: 3D Bioprinting, Skin Model, Bioink, Tissue Engineering, Drug Testing, Disease Modeling, Regenerative Medicine.