INTRAMEDULLARY SPINAL GANGLIOGLIOMA WITH ANAPLASIA AND KIAA1549-BRAF FUSION, AN UNCOMMON ENTITY: A CASE REPORT
Dr. G. P. Mishra, Dr. Simin Laiq, Dr. Zahra Al Hajri, Dr. Mohammad Al Tamimi, Dr. Samit Biniwale, Dr. Chandrasekhar B. V. K. Yandrapati, Dr. Hotchand Maheshwari and Dr. Neeraj Salhotra*
ABSTRACT
Ganglioglioma is a rare, slow-growing primary central nervous system (CNS) tumor which most frequently occurs in the temporal lobes, typically resulting in seizures. Ganglioglioma of the spinal cord is exceedingly rare, only approximately 178 cases of spinal cord ganglioglioma have been reported, mostly in children or young adults. The gold Standard of treatment is gross total resection; however, the optimal treatment in the setting of subtotal resection has not been clearly established. We report an unusual case of an intramedullary cervical spinal cord ganglioglioma with anaplasia and KIAA1549-BRAF fusion in a 4-year-old boy who underwent subtotal resection followed by adjuvant radiotherapy.
Keywords: Ganglioglioma with anaplasia, KIAA1549-BRAF fusion.
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