REVIEW STUDY ON GELASTIC SEIZURES

Yalamanchili Roshini, Macharla Eswar Subhash, Thiruveedula Kumari, Anasuri Kusuma Sri, Yogendar Yaswanth Babu Pamula, Sreenu Thalla, Puttagunta Srinivasa Babu and *Pusuluri Siva Krishna

ABSTRACT

Gelastic seizures, characterized by sudden bursts of laughter or giggling, represent a unique and often misdiagnosed form of epilepsy. This review aims to synthesize current understanding of gelastic seizures, including their clinical presentation, etiology, pathophysiology, and management strategies. We explore the diverse causes, ranging from hypothalamic tumors to genetic factors, and highlight the challenges in diagnosis due to their atypical presentation. Furthermore, we examine the neurophysiological mechanisms underlying these seizures, emphasizing the role of the hypothalamus and limbic structures. Treatment modalities, including antiepileptic drugs and surgical options, are discussed in detail, alongside their efficacy and associated outcomes. This comprehensive review underscores the need for heightened awareness among clinicians to facilitate timely diagnosis and improve patient management, ultimately enhancing the quality of life for individuals affected by gelastic seizures.

Keywords: Gelastic seizures, epilepsy, hypothalamus, limbic structures.