PIONEERING NEW FRONTIERS: BREAKTHROUGHS AND BARRIERS IN CLINICAL TRIALS

Kashish Kaithwas*, Akash Yadav and Dinesh Kumar Jain

ABSTRACT

Clinical trial design and interpretation are fundamental components of evidence based medicine, serving as the basis for well-informed treatment plans and healthcare decisions. In order to reduce bias and guarantee the validity of study findings, this review article examines the fundamental components of clinical trial design, such as randomization, blinding, control groups, sample size calculation, and ethical issues. The essay also looks at how clinical trial results are interpreted, emphasizing the significance of statistical significance, clinical relevance, and the possibility of confounding variables. It also covers issues including the impact of protocol violations, generalizability, and incorporating trial results into clinical practice. By thoroughly examining both design and interpretation, this review seeks to offer insightful information to researchers, physicians, and policymakers in optimizing the quality and applicability of clinical trial results.

Keywords: Clinical Trial Design, Trials of Adaptation, Significance Of Clinical trials.