FORMULATION, DEVELOPMENT AND EVALUATION OF CAPSICUM EXTRACT CAPSULES DELIVERY SYSTEM AS AN ADVANCED PHYTOTHERAPY APPROACH FOR TONIC AND NATURAL STIMULANT ACTIONS

Prof. Dr. Mahmoud Mahyoob Alburyhi* and Prof. Dr. Amina El-Shaibany

ABSTRACT

Capsicum, commonly known as Chili peppers, has a long history of Medicinal properties, primarily as a digestive, thermogenic, carminative, stimulant, cardiotonic, antipyretic, serdorific, rubefacient & sialagogue. Capsicum annuum is the most widely cultivated and distributed species in Yemen. Paprika, Capsicum annuum L. (Solanaceae) is one of the oldest, most important and widely used carotenoid food colorants. Capsicum is a remarkable whole-body stimulant that can boost blood flow, tone the nervous system, relieve indigestion, promote sweating, help to cauterize and heal ulcers, ease persistent pain and fight off infection. Because Capsicum boosts peripheral circulation and stimulates organ secretion, it expedites the therapeutic delivery and action of other herbs. Capsicum stimulates everything from blood flow to peristaltic action in the stomach, to intestinal transit time. The remarkable ability of Capsicum to stimulate organ secretion and even heart action makes it one of the strongest natural stimulants known. Several different kinds of herbal blends targeting various body systems will utilize Capsicum to boost the formulations efficacy. A Capsicum was formulated as capsules and evaluated for organoleptic properties and other evaluation parameters. It was concluded that among the all formulations of Capsicum extract capsules the F1 was found to be as an optimized capsules according to drug release percentage 90% within 60 minutes, so the F1 was the best formulation of Capsicum extract capsules delivery system as an advanced phytotherapy approach for tonic and stimulant actions.

Keywords: Capsicum, Extract, Capsules, Tonic, Natural Stimulant actions.