EMULGEL FORMULATION: A PROMISING STRATEGY FOR ENHANCED DRUG PENETRATION AND EFFICACY

Anil Prajapati*, Dr. M. K. Gupta, Ashish Prajapati, Suraj Kumar and Akshay Gond

ABSTRACT

Topical drug delivery offers advantages such as site-specific action, avoidance of first-pass metabolism, and improved patient compliance. Conventional formulations like creams and ointments often suffer from poor drug solubility, limited skin penetration, and instability. Emulgels, which combine the properties of emulsions and gels, provide an effective alternative by enhancing solubility, skin retention, and controlled drug release. This review outlines the formulation components, methods, and mechanisms that contribute to the superior performance of emulgels in transdermal and topical applications. Evaluation parameters such as viscosity, pH, drug content, and skin irritation—are discussed to ensure quality and safety. Emulgels are especially effective in delivering anti-inflammatory, antifungal, antimicrobial, and cosmeceutical agents. Recent advancements, regulatory considerations, and formulation challenges are also addressed. With their multifunctionality and improved therapeutic profiles, emulgels show strong potential in advancing dermatological drug delivery.

Keywords: Emulgel, drug delivery, Transdermal delivery, Novel drug delivery systems.