PHYSICO-CHEMICAL CHARACTERIZATION OF SIDDHA HERBAL FORMULATION NAANALKARUMBU CHOORANAM: AN APPROACH TO STANDARDIZATION

Dr. Moovendan Ramalingam* and Dr. Bavani Perumal

ABSTRACT

Naanal Karumbu Chooranam is reputed drug mentioned in classical Siddhaliterature for the treatment of obesity. The main component of Naanal Karumbu Chooranam is the stem of Saccharumspontaneum. The aim of thispresent study was carried out to standardize the drug Naanal Karumbu Chooranamby evaluating its Organoleptic characters, Physico chemical properties and modern scientific instruments like, SEM (Scanning Electron Microscope), Fourier Transform - Infra Red (FTIR) Spectroscopy. Organoleptic characters such as colour, odour, taste, particle size and Physico-Chemical Characters like ash Values, pH value, solubility were analyzed. The total ash value was found to be 6.68%w/w, acid insoluble ash value is 1.29%w/w and moisture content is 4.94% w/w. The pH value is 5.53. The water soluble extractives and alcohol soluble extractives were found to be 23.83% w/w and 17.27% w/w. FT-IR spectroscopy showed the presence of functional groups like phenols, alcohols, amines, aliphatic amines, aromatic amines, amides and alkyl halides. These functional groups are key factors for Hypolipidemicactivity. SEM analysis of the drug indicated the existence of nanoparticles. Nano particle sizes are 39.7nm, 79.4 nm and 107 nm.

Keywords: Physico-chemical properties, ash values, FT-IR spectroscopy, SEM.