AMIDARONE-INDUCED HYPERTHYROIDISM: CARDIOLOGICAL ASPECTSO

Abdikadirova Tursinay*, Alieva Anna, Trigulova Raisa and Nasirova Khurshida

ABSTRACT

Amiodarone-induced hyperthyroidism (AIH) is a serious complication in patients with arrhythmias undergoing long-term antiarrhythmic therapy. This article presents data from a retrospective observation of 16 patients with AIH who were hospitalized in the cardiology department. Hormonal parameters (TSH, free T4, T3, anti-TSH receptor antibodies) and cardiological indicators (heart rate, heart rate variability — SDNN) were analyzed before and after 6 months of antithyroid therapy. The results demonstrated a significant improvement in both hormonal and cardiac status, indicating the necessity of timely diagnosis and treatment of AIH. Particular attention is paid to the differential diagnosis of AIH types, treatment selection, and evaluation of effectiveness from the cardiologist's perspective.

Keywords: Amiodarone, thyroid gland, Amiodarone-induced hyperthyroidism, Antiarrhythmic therapy, Heart rate variability.