A REVIEW ON THE IMMUNOMODULATORY POTENTIAL OF PLANT BASED EXTRACTS IN PRECLINICAL MODELS

N. Thripthi* and P. J. Yakshith

ABSTRACT

In addition to physical and chemical barriers to infections, the immune system includes two primary defence mechanisms: innate immunity and adaptive immunity. Innate immunity is the body's first line of defence against an invading infection. It's a non-memorable immunological reaction that starts minutes or hours after aggressiveness. Adaptive immunity, on the other hand, is antigen-dependent and antigen-specific, with the ability to remember the antigen, allowing the host to build a more quick and efficient immune response when exposed to it again. When the immune system targets self-molecules as a result of a breakdown in immunological tolerance to autoreactive immune cells, autoimmune illness develops. The objective of this review is to give information on the use of phytochemicals to treat autoimmune illnesses that impact the immune system.

Keywords: Immunosupressants, autoimmune disease, immunostimulants, cytokines.