EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

“REYE’S SYNDROME – OFTEN MISSED IN PATIENTS OF ACUTE FEBRILE ENCEPHALOPATHY”

Dr. Bhupesh Jain*, Dr. Suresh Goyal and Dr. B. L. Meghwal

ABSTRACT

1. Background and Objective: - Acute Febrile Encephalopathy (AFE) defined as fever associated with acute depression of consciousness or mental deterioration with or without seizure, motor and/ or sensory deficit and total duration of illness one week or less. Reye’s syndrome, an encephalopathy with fatty infiltration of the viscera is an acute illness, characterized by profound disturbance in consciousness, fever, vomiting, convulsion, hypoglycemia with fatty infiltration of the viscera. This study was conducted to find out clinical and etiological profile & outcome of Acute Febrile Encephalopathy in south Rajasthan. 2. Methods:-This study was Hospital based prospective study from July 2015 to Dec. 2015. All patients of AFE with raised liver enzymes (>3 fold), raised serum ammonia (>50 mol/L), abnormal coagulogram, anicteric and usually a history of fever in recent past were diagnosed as Reye’s syndrome. 3. Results: - A total of 85 patients of AFE were admitted, 14 cases (16.47%) were diagnosed as Reye’s syndrome. Clinical profile of patients of Reye’s Syndrome include Fever and altered sensorium 14 (100%), Generalized convulsions 13 (92.85%), raised ICT 9 (64.28%), Protracted vomiting 14 (100%). Most of the patients {12 (85.71%)} had hypoglycemia. All patients of Reye’s syndrome had SGPT level >1000 IU/L, anicteric and raised Ammonia level. Seven patients show cerebral edema on neuroimaging. Four patients had raised CSF pressure. Case fatality rate (78.57%) was high in patients of Reye’s syndrome compared to Suspected viral encephalitis, Cerebral Malaria and Pyogenic Meningitis. 4. Conclusion: - Reye’s syndrome was seen in 14 patients (16.47%) of AFE. Increasing awareness of this syndrome and a high index of suspicion are important for timely diagnosis. This is important because management has to be energetic, if the mortality from this disease is to be reduced.

Keywords: Acute Febrile Encephalopathy; Reye’s syndrome; Cerebral Malaria; Suspected viral encephalitis; Pyogenic Meningitis.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • EJPMR: JANUARY ISSUE PUBLISHED

    JANUARY issue has been successfully launched on 1 JANUARY 2023.

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 January 2023 Issue has been Published, Kindly check it on https://www.ejpmr.com/issue

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database