CRINUM ASIATICUM- AN EMERGING ANTIMICROBIAL HERBAL CREAM

Samiksha Palkar*, Kajal Khade, Aayesha Mujawar, Snehal Kakde, Vinod Pattankude and Dhanraj Jadge

ABSTRACT

Microbial infections continue to be one of the most urgent global health issues, impacting healthcare systems globally and affecting millions of people each year. Bacteria, viruses, fungi, and parasites are examples of harmful microorganisms that have a broad range of effects on human health, from minor skin infections to serious systemic disorders. Developing efficient surveillance, preventive, and treatment techniques requires an understanding of the global effects of microbial diseases. The current work performed by formulating and its evaluation of an antimicrobial herbal cream. Most currently available creams are made with synthetic drugs and can provide relief from skin infections; however, they often cause side effects like itching or allergic reactions. Crinum asiaticum is a medicinal plant recognized for its wide range of bioactive constituents and has shown strong antimicrobial activity in traditional healing practices. Phytochemical studies have identified the presence of alkaloids, flavonoids, and phenolic compounds, which are believed to play a key role in its biological effects. This study focuses on the formulation and evaluation of a topical herbal cream for its antimicrobial efficacy. Ethanollic extract of the plant's leaves were tested against common pathogenic microorganisms, including Staphylococcus aureus and Salmonella typhimerium using the agar well diffusion method. The formulated cream exhibited substantial antimicrobial activity. Stability testing indicated that the cream retained its effectiveness and physical properties under various storage conditions. These findings suggest that Crinum asiaticum based herbal cream holds promise as a natural, cost-effective and alternative treatment for microbial skin infections. Further studies are recommended to validate its safety and therapeutic potential.

Keywords: Herbal cream, Crinum asiaticum, Staphylococcus aureus, Salmonella typhimerium.