CLINICAL SIGNIFICANCE OF PRIMARY TUMOR RESECTION IN METASTATIC COLORECTAL CANCER

Nader Abdullah, Bassam Saad and Ibrahem Shamout*

ABSTRACT

Objective: The aim of the present study is to determine the effect of primary tumor resection on overall survival and progression-free survival in metastatic colorectal cancer. Methods: The study sample included 561 patients with metastatic CRC who attended the Medical Oncology Department, Lattakia University Hospital during the period 2015- 2021 divided into two groups; with and without primary tumor resection. OS and PFS were studied and compared between groups in terms of mean and standard deviation. Results: It was found that there was a significant difference P<0.05 in the OS and PFS rates between the two groups, as the patients who underwent primary tumor resection had higher OS and PFS. Conclusion: Primary tumor resection improves OS and PFS rates in patients with metastatic CRC.

Keywords: metastatic colorectal cancer, overall survival, progression-free survival.