THERAPEUTIC USES OF NIGELLA SATIVA: A COMPREHENSIVE REVIEW

*Dr. Md. Nadeem Akhter and Dr. Khatiba Aatka Maryam

ABSTRACT

Nigella sativa, commonly known as black seed or Shoneez in Unani medicine, is a medicinal plant with a rich historical and therapeutic legacy across various traditional systems, including Unani, Ayurveda, and Tibb-e-Nabwi (Prophetic Medicine). Revered for centuries as a panacea, its seeds and oil have been used to treat a wide array of ailments. This review synthesises classical Unani literature, such as texts by Ibn Sina and Al-Razi, with recent evidence-based studies to elucidate the pharmacological properties, phytochemistry, and clinical applications of Nigella sativa. The bioactive compound thymoquinone is highlighted as a key contributor to its therapeutic effects, including antioxidant, anti-inflammatory, antimicrobial, antidiabetic, anticancer, and cardioprotective activities.[1] While classical Unani texts emphasise its holistic benefits, modern research validates many traditional claims, though gaps in clinical standardisation and large-scale trials remain. This paper aims to bridge traditional wisdom with contemporary science, providing a comprehensive resource for researchers and clinicians.

Keywords: Nigella Sativa, Black Seed, Thymoquinone, Unani Medicine.