HIDDEN BURDEN OF HYPONATREMIA IN TORSEMIDE-PRESCRIBED PATIENTS: AN OUTPATIENT-BASED STUDY AT IGMC SHIMLA

Dr. Kanika Khamb and Dr. Mayank*

ABSTRACT

Background: Torsemide is a loop diuretic widely used in outpatient management of heart failure, liver disease, and chronic kidney disease. It is associated with adverse effects, including hyponatremia. Understanding the prevalence and severity of this condition in the outpatient population is crucial for timely management. Objectives: To determine the prevalence and severity of hyponatremia in patients on torsemide therapy presenting to the Medicine OPD at IGMC Shimla and to identify associated risk factors. Methods: A cross-sectional study involving 150 adult patients taking torsemide for ≥2 weeks was conducted. Serum sodium levels were measured and categorized. Demographic, clinical, and therapeutic data were analyzed for associations. Results: Hyponatremia was observed in 54 (36%) of patients. Mild hyponatremia was the most common (25.3%), while moderate (8%) and severe (2.7%) forms were less frequent. Risk factors included older age, high torsemide dose, and comorbid heart failure. Conclusion: Hyponatremia, particularly in mild form, is common in outpatients on torsemide. Regular sodium monitoring and attention to dosage and comorbidities are essential to mitigate risks.

Keywords: Hyponatremia, Torsemide, Prevalence, Loop Diuretic, IGMC Shimla, Outpatient.