PROFILE OF INTERISTIAL LUNG DISEASES AT TERTIARY CARE CENTRE OF NORTHERN INDIA

Kumar Adesh (MD), *Yadav Prashant (MD), Gupta K. Ashish (MD), Gautam K. Aditya (MD), Kumar Anand (MD) and Chaudhri Sudhir (MD) 

ABSTRACT

Background: Interstitial lung disease (ILD) is a heterogeneous group of lung diseases which are challenging to the clinicians. There is limited data on the presentation and diagnosis of these patients from India. The present study was planned to analyse the spectrum of ILD encountered at a tertiary referral centre in India to determine the clinical profile of the disease. Material and Methods: This study includes 116 patients diagnosed to have ILDs during the years 20013–2015 at tertiary care centre of north India. The diagnosis of ILD was based on clinical, radiological parameters, laboratory parameters, spirometric parameters and histopathology wherever available. Classification of ILD was done as per The American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of Idiopathic Interstitial Pneumonias 2001 guidelines were used in the diagnosis. Result: The overall mean age at presentation was 45.24 years, 54.83 years in IPF, 44.60 years in HSP, 43.60 years in NSIP and 41.56 years in Sarcoidosis. Of the 116 ILD cases there were 70 male (60.34%) and 46 (39.66%) females. The overall mean duration of symptoms at diagnosis was 2.47 years, 1.5 years in IPF, 1.2 years in HSP, 1.5 years in NSIP and 3 years in Sarcoidosis. The most frequent presenting symptom in the ILD was cough present in 98 (84.45%), followed by exertional dyspnoea in 86 (74.13%). Conclusion: Interistial pulmonary fibrosis is the most common and Hypersensitivity Pneumonitis is the second common Interistial Lung Disease in our study. Being progressive disease most of the patients presented to us in advance stage of disease and in most of the cases anti tubercular treatment was started by the treating physician without being extensive evaluation because of lack of awareness among physicians.

Keywords: Interistial Lung Disease, Idiopathic Pulmonary Fibrosis, Diffuse Parechymal Lung Disease.