PHYTOSOMES: A NOVEL STRATEGY TO IMPROVE BIOAVAILABILITY OF ACTIVE CONSTITUENTS

Nirmala*, Piyush Kaushal, Swapanjot Kaur, Gurprasad Singh, Priyanka Thakur, Abhimanyu Bhardwaj

ABSTRACT

"Phyto" refers to a plant, while "some" implies a cell. The term "autosomes" describes a novel patented method that increases bioavailability and absorption by combining standardised botanical extracts or water-soluble botanical components with phospholipids to create lipid-compatible molecular complexes. Based on recent advances and research by many researchers, the transdermal method has been carefully studied to determine its potential as a delivery system for botanical ingredients. Plant-based products and extracts are increasingly being recognized for their potential as nutritional supplements in managing inflammation, toxicity, malignancies, weight loss, and various chronic diseases or conditions. However, these products often suffer from bioavailability and stability issues. After separation, plant material will not be stable and will not pass through biofilms. Through practice, these activities are reduced to a reasonable level. To improve their suitability for drug administration, phytosomes—also known as phytosome technology—increase the hydrophilicity of medications that are otherwise exceedingly lipophilic. Also, they make hydrophilic plant components more lipophilic, which improves their transport across biological systems. It has been determined that the plant body can be used for cosmetic purposes. This article not only compares liposomes and phytosomes but also highlights the latest advancements in phytosome technology, with particular emphasis on transdermal drug delivery systems and phospholipid complexes. Many commercial products, including ginkgo, milk thistle, and tea tree, contain phytopharmaceutical compounds.

Keywords: Phytosome, Bioavailability, phospholipids, autosomes.