A REVIEW OF AZITHROMYCIN USED IN COVID 19

Akib Kanth* and Muskan Sharma

ABSTRACT

The Strategic Plan for Biodefense Research of the U.S. Department of Health and Human S
ervices emphasizes the
urgent need for medications that can efficiently target many pathogens as part of our readiness for infectious
disease threats. Azithromycin is a notable broad spectrum therapeutic highlighted in the University of Oxford’s
RECOVERY t rial, yet it was notably absent from the World Health Organization’s SOLIDARITY trial. This review
explores the pharmacological versatility of azithromycin, including its antibiotic, antimalarial, and antiviral
properties, and discusses its history as amon g the most frequently repurposed drugs within the macrolide class.
Additionally, we assess the clinical and socio economic significance of azithromycin in the context of respiratory
pandemics, presenting a model that clarifies its combinatorial way of acti on against COVID 19 pneumonia.

Keywords: .