CURRENT TRENDS IN COMPUTER - AIDED DRUG DESIGN; A COMPREHENSIVE REVIEW

Sandeep Prakash*, Deepa Devi, Ankit Sharma, Jitendra Kumar, Jitendra Kanoujiya, Rupali, Sudhanshu
Kanaujiya, Sana Ansari, Varun Singh and Zuveriya Mirza

ABSTRACT

The process of discovering and developing a new medication is often seen as a lengthy and expensive endeavors.
As a result, computer-aided drug design methods are now frequently utilized to improve the efficiency of the drug
discovery and development process. Various CADD approaches are regarded as potential techniques based on their
needs; nevertheless, structure-based drug design and ligand-based drug design approaches are well-known as
highly efficient and powerful strategies in drug discovery and development. Both of these approaches may be used
in conjunction with molecular docking to conduct virtual screening for the purpose of identifying and optimizing
leads. In recent years, computational tools have become increasingly popular in the pharmaceutical industry and
academic fields as a means of improving the efficiency and effectiveness of the drug discovery and development
pipeline. In this post, we'll go over computational methods, which are a creative way of discovering new leads and
assisting in drug discovery and development research.

Keywords: Computer Aided Drug Design (CADD); Structure-Based Drug Design; Ligand-Based Drug Design; Virtual Screening and Molecular Docking.