A STUDY ON PRESCRIBING PATTERN OF CARDIOVASCULAR DRUGS & POTENTIAL DRUG - DRUG INTERACTIONS IN AN INPATIENT CARDIOLOGY UNIT OF A CARDIAC - CARE HOSPITAL AT TIRUPATHI.
Bandla Aswani*, Purushothama Reddy K., P. Yanadaiah and S. Sujatha
Cardiovascular disorders (CVD’s) are estimated to be the leading cause of mortality worldwide. A prospective
observational study was carried out at inpatient department of cardiology in tertiary care hospital, Tirupathi from
December 2012 – May 2013 during regular ward rounds. A survey of prescribing patterns was undertaken among
inpatients admitted with cardiovascular disease. The demographic details and treatment data of the 180 inpatients
were collected in a specially designed proforma. The average age of study population was found to be 59.06 ± 1.8
years. Subjects of age groups > 40 (92.77 %) were found to be more susceptible to CVD and majority of them were
males 46.66 %. Average number of cardiovascular drugs per patient was 5.58. 57.05 % of the drugs prescribed
were from the Indian 2011 list of essential drugs. Polypharmacy was observed in 68.33 % (123) prescriptions. The
prescription rate of antiplatelet, anticoagulant and fibrinolytics were 22.46 %, followed by 20.07 % of antianginal
drugs. The prescribing frequency of antianginal drugs 88.57 % during discharge time was higher. 390 potential
drug - drug interactions were screened. Medication adherences were more in male patients 56.12 % among the
86.66 % of follow up patients. This preliminary study reveals a lot of scope for CVD prevalence studies in India
and used for implementation of an alert guidelines.
Keywords: Cardiovascular diseases (CVD), cardiovascular drugs, Prescription pattern, drug - drug interactions & medication adherence.
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