RECENT TRENDS IN NOVEL OPHTHALMIC DRUG DELIVERY SYSTEM- A SHORT REVIEW
Ophthalmic drug delivery is among the most interesting and challenging endeavors facing the pharmaceutical scientist. The anatomy, physiology, and biochemistry of the eye renders this organ more impervious to foreign substances. Their is significant challenge for the formulator to circumvent the protective barriers of the eye without causing permanent tissue damage. Development of newer, more sensitive diagnostic techniques and novel therapeutic agents continue to provide ocular delivery systems with high therapeutic efficacy. The major problem with the conventional dosage forms is the bioavailability of drug, which were improved ion last three decades by common method i.e. adding viscosity-enhancing agent or mucoadhesive polymers into drug formulation. The specific aim for designing a therapeutic system is to achieve an optimal concentration of a drug at the active site for the appropriate duration.
Keywords: Novel ophthalmic drug delivery system, conventional dosage form, in-situ gelling system.
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