EFFECT OF MINT LEAVES EXTRACT ON MDR PATHOGENS: A COMPARATIVE STUDY
Bansode D.S.* and Chavan M.D.
In the present study antimicrobial activity of crude Mint (Mentha arvensis) leaves extract observed in comparison with Standard antibiotics Cholistin, Erythromycein, Ciprofloxin, Methicillin, Ampicillin and Cephalosporin. In this study, the antimicrobial efficacy of crude Mint leaves extract was examined and tested against following bacterial cultures those were Salmonella typhi (5 strains), E.coli (8 strains), Shigella sonnei (7 strains) and Shigella flexinary (8 strains). As microorganisms becoming resistant to present day antibiotics, our study focuses on antimicrobial activity of Mint leaves extract in comparison with standard antibiotics against selected enteric pathogens. Antimicrobial analysis was done by using agar well diffusion method against selected enteric pathogens. Natural product may act as an substitute for antibiotics and chemotherapeutic agents in certain conditions. Historically, plants have provided a source of motivation for novel drug compounds, as plant derived medicines have made great contributions to human health and welfare. Medicinal plants correspond to a rich source of biological agents which play very important role in a number of functional and regulation mechanisms occurring in plant as well as in animal body. In the present investigation, Mint leaves extract showed highest antibacterial activity against Salmonella typhi strain V (ZOI- 16mm), E.coli strain VII (ZOI- 18mm), Shigella sonnei strain VI (ZOI- 20mm) and Shigella flexinary strain V (ZOI- 16mm). Salmonella typhi strain III, Shigella sonnei strain III, Shigella flexinary strain VI showed no ZOI with Mint leaves extract.ie these strains were observed resistant to Mint leaves extract. All bacterial strains were also observed resistant to all tested antibiotics. So the present study shows that, these tested multidrug resistant organisms were observed resistant to studied standard antibiotics but those were observed sensitive to crude Mint leaves extract.
Keywords: Antimicrobial activity, Mentha arvensis, Enteric pathogens, Standard antibiotics etc.
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