EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EFFECT OF MINT LEAVES EXTRACT ON MDR PATHOGENS: A COMPARATIVE STUDY

Bansode D.S.* and Chavan M.D.

ABSTRACT

In the present study antimicrobial activity of crude Mint (Mentha arvensis) leaves extract observed in comparison with Standard antibiotics Cholistin, Erythromycein, Ciprofloxin, Methicillin, Ampicillin and Cephalosporin. In this study, the antimicrobial efficacy of crude Mint leaves extract was examined and tested against following bacterial cultures those were Salmonella typhi (5 strains), E.coli (8 strains), Shigella sonnei (7 strains) and Shigella flexinary (8 strains). As microorganisms becoming resistant to present day antibiotics, our study focuses on antimicrobial activity of Mint leaves extract in comparison with standard antibiotics against selected enteric pathogens. Antimicrobial analysis was done by using agar well diffusion method against selected enteric pathogens. Natural product may act as an substitute for antibiotics and chemotherapeutic agents in certain conditions. Historically, plants have provided a source of motivation for novel drug compounds, as plant derived medicines have made great contributions to human health and welfare. Medicinal plants correspond to a rich source of biological agents which play very important role in a number of functional and regulation mechanisms occurring in plant as well as in animal body. In the present investigation, Mint leaves extract showed highest antibacterial activity against Salmonella typhi strain V (ZOI- 16mm), E.coli strain VII (ZOI- 18mm), Shigella sonnei strain VI (ZOI- 20mm) and Shigella flexinary strain V (ZOI- 16mm). Salmonella typhi strain III, Shigella sonnei strain III, Shigella flexinary strain VI showed no ZOI with Mint leaves extract.ie these strains were observed resistant to Mint leaves extract. All bacterial strains were also observed resistant to all tested antibiotics. So the present study shows that, these tested multidrug resistant organisms were observed resistant to studied standard antibiotics but those were observed sensitive to crude Mint leaves extract.

Keywords: Antimicrobial activity, Mentha arvensis, Enteric pathogens, Standard antibiotics etc.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )