EFFICACY OF SPIRULINA CAPSULES AS AN ADJUVANT IN MANAGEMENT OF LEUKOPLAKIA

Amara Deepika Jagannathan, Dr. Sindhu Poovannan*, Dr. G. S. Asokan, Dr. Narmatha N. and Dr. Angelinteena S.

ABSTRACT

Aim: A premalignant lesion which is closely associated with tobacco usage is oral leukoplakia. Evaluating the efficacy of spirulina algae capsules (500 mg) as an adjuvant in the management of oral leukoplakia. Materials and Methods: The study comprised 20 patients with a clinical diagnosis of oral leukoplakia. Over the course of 21 days, patients received 500 mg spirulina oral capsules, and clinical parameters were assessed at day 0, 7, 14, and 21 intervals. Chi square was used for data analysis. P value was set at 0.005. Results: Post hoc test showed statistically significant improvement (p=0.000) of the mean rank of all parameters from day 0 to day 21. Conclusion: Higher lesion severity aligns with elevated burning sensation suggesting that lesion progression intensifies sensory symptoms. This study shows clinically significant improvements in the symptoms like burning sensation, inflammatory signs and size of lesion with Spirulina (500 mg) oral capsules as an adjuvant.

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