EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

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Abstract

OPEN LABELLED CLINICAL TRIAL TO ESTABLISH THE STANDARD TREATMENT PROTOCOL FOR PARKINSON’S DISEASE (KAMPAVATA).

Patel Kishore*, Charde Vaibhav, Patel Roopali, Prajapati P. K. and Baghel M. S.

ABSTRACT

Background: Parkinson's disease (Kampavata) is a neurodegenerative condition which affects the basal ganglia and which presents with differing combinations of bradykinesia, rigidity, tremor and loss of postural reflexes also commonly observed in geriatric population. Researches conducted so far in the field of this disease in both Ayurveda and contemporary systems of medicine, it still remains the established risk factor for the geriatric population after the age of 50 years. Till date there is no definite curative treatment available in modern medicine. Aims: To access the clinical efficacy of the developed treatment protocol. Material and methods: In this trial, ten patients having sign and symptoms of PD were subjected to open labelled clinical trial with developed treatment protocol and internal medication. Assessment was done on the basis of relief in sign and symptom of disease. Effect of therapy on Hoehn & Yahr’s Staging System was also evaluated by means of statistical analysis. Results: Developed protocol showed statistically significant changes in sign and symptoms. Moderate improvement was seen in majority of the patients belonging to stage 3 while marked improvement was seen in all patients in stage 4 of PD. Overall effect of the therapy provided marked improvement in majority of the patients. Conclusion: The study establishes that the developed treatment protocol has definite role in the management of PD and it also helps to improve the quality of life of the patients.

Keywords: Parkinson's disease, Ayurveda, Protocol, Kampavata, Neurodegenerative disorder.


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