IMMUNOLOGICAL POTENTIAL OF PLATELETS – A META-ANALYSIS

Neha Pant, Ekta A. Andriyas, Deepak Sharma, Munzali Hamisu Umar, Arun Kumar Saxena and Imran Hussain*

ABSTRACT

Innate cells are crucial for the initial stages of pathogenic invasion because they express different pattern recognition receptors (PRRs). By identifying dangerous substances generated by the host body through danger-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs), PRRs aid in recognizing microbial invasion. The innate immune system's cells react to danger by releasing or producing molecules for effector function, which involves organising the recruitment and activity of several specialised cell populations that use phagocytosis and lytic functions to combat invasive pathogens. Examples of these molecules include defensins, cytokines, and chemokines. Innate cells' PRRs play a crucial role in starting some cells' ability to convey antigens to lymphocytes. Adaptive immune cells, known as lymphocytes (T and B cells), offer an additional layer of defence to a host. Thrombocytes can be round, oval, spindle, or spiking cells with long cell processes. They are sized similarly to lymphocytes. A surface-connected canalicular structure appears to exist in the cytoplasm of thrombocytes. A wide range of bioactive proteins, including those that are antibacterial, inflammatory, and immune-modulating compounds, can also be produced and released by thrombocytes.

Keywords: Adaptive immune cells, known as lymphocytes (T and B cells), offer an additional layer of defence to a host.