ENHANCING OUTCOMES THROUGH PATIENT-CENTRIC CLINICAL TRIALS: EMPOWERING PARTICIPANTS FOR IMPROVED RESULTS

*Muskan Abdul Khadar Shaikh, Kondakamarla Sahul, Rushikesh Gopal Bavaskar, Tushar Madhukar Patil

ABSTRACT

The paradigm of clinical trials is undergoing a significant transformation with a shift towards patient-centric models. This review explores how empowering participants through patient-centric clinical trials can lead to improved outcomes. By focusing on patient preferences, needs, and experiences, these trials enhance participant engagement and contribute to more relevant and actionable data. Patient-centric trials involve principles such as patient involvement in trial design, flexible protocols, transparent communication, and a supportive environment. Benefits include increased recruitment and retention, enhanced data quality, more relevant outcomes, and improved participant experiences. Strategies for implementing these approaches include establishing patient advisory boards, personalizing communication, offering flexible scheduling, and providing support services. The review also highlights successful case studies, demonstrating the practical applications and benefits of patient-centric models. As the field evolves, addressing challenges and developing standardized frameworks will be crucial for maximizing the potential of patient-centric clinical trials.

Keywords: Patient-Centric Clinical Trials, Participant Empowerment, Trial Design, Patient Engagement, Clinical Research, Patient Preferences, Trial Outcomes, Flexible Protocols, Support Services, Recruitment and Retention.