A PROSPECTIVE OBSERVATIONAL STUDY ON CLINICAL SAFETY AND EFFICACY OF MEDICATIONS USED IN THE MANAGEMENT OF CHRONIC LIVER DISEASE

*Ponnala Brahmachary, Nerella Bhavana, Puluguri Sadguna, Raju Pranalika, Dr. G. S. Sameer Kumar, Dr. M. Rama Krishna

ABSTRACT

Background: Chronic liver disease is a continuous process of inflammation and destruction, which leads to fibrosis and cirrhosis. So, however, many drugs are prescribed to overcome the diseased condition of patients. As a result, the safety and efficacy of the drugs must be evaluated. Method: The study includes 65 patients. The study lasted six months in a tertiary care hospital. Results: Among the 65 patients, 54 were male and female. The patient age group was categorized into groups, and the highest number of patients were observed between the age groups 50-60 and 60-70. Out of 65 patients, 9 had no comorbidities, and 54 had comorbidities, out of which 49 were male and 5 were female. Out of the 65 individuals, 60 did not report any side effects, and the efficacy of the drug was evaluated by comparing the values of LFT before and after usage of the drug. Conclusion: In CLD patients, the most commonly used medications were ursodeoxycholic acid and s-adenosyl methionine. This resulted in decreased ALT and AST levels in old patients who were taking the medications.

Keywords: Among the 65 patients, 54 were male and female.