EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

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 ISSN 2394-3211

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Abstract

INTRATYMPANIC STEROID INJECTION IN THE TREATMENT OF OTITIS MEDIA WITH EFFUSION

*Dayana Khalouf, Fayez Al Alouny and Yasser Ali

.

ABSTRACT

Study Background: Otitis Media with effusion is a common problem, especially in children, resulting from the
poor function of the Eustachian tube. It is associated with conductive hearing loss and tinnitus, and it is the most
common cause of hearing deficiencies in children, which negatively affects their linguistic and social development.
Objective: To determine the effectiveness of Intratympanic steroid injection as a new therapeutic approach for
Otitis Media with effusion. Materials and Methods: A prospective, observational study, coupled with a control
group. The number of patients reviewed was 30 (60 ears), of which 56 ears met the criteria for inclusion and
exclusion, as 4 ears were intact. They were divided into two groups according to a random distribution schedule:
the first group (A) received budesonide injections into the tympanum, and the second group (B) had ventilation
tubes installed. Along with the required surgical procedure for each patient. The first group received injections four
consecutive times over four weeks. Patients were evaluated based on the results of audiometry, impedance, and
complications after more than four months. Results: The degree of hearing improvement was better in the group
that received the injections (P-value = 0.002), and the postoperative complications were lower, but the possibility
of recurrence was higher (P-value = 0.0001). Conclusions: Intratympanic Steroid injection are safe and rapid
intervention that benefits the treatment of otitis media with effusion, but there is a possibility of recurrence.

Keywords: Otitis Media with effusion, Intratympanic steroid injection, Budesonide.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia